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A compound found in cannabis could protect one of the world’s most dangerous fungal pathogens.

Cryptococcus neoformans causes life-threatening meningitis.

In lab tests, researchers found that two cannabis compounds—cannabidiol (or CBD) and cannabidivarin (or CBDV)—killed the fungus more effectively than commonly used antifungal drugs. The compounds also worked on common fungi that cause skin infections like jock itch and athlete’s foot. The researchers tested the treatment on wax moth larvae, which have an immune system similar to ours. Larvae treated with CBD survived at higher rates than those given a standard antifungal drug, and almost as well as uninfected larvae. The cannabis compounds appear to work by damaging the fungus’s cell membranes and disrupting its energy production.

This study shows that CBD might be a powerful treatment for skin infections, and possibly more, if further research confirms its safety and effectiveness in humans. CBD is also knowns for its anti-inflammatory, anti-anxiety, and neuroprotective properties. It's already approved in some countries as a treatment for rare forms of epilepsy, such as Dravet syndrome, where it helps reduce the frequency and severity of seizures. Studies also suggest it may ease symptoms of anxiety, insomnia, and chronic pain, and may support recovery from conditions involving inflammation, like arthritis or multiple sclerosis. Unlike THC, CBD does not cause a high, which makes it more suitable for daily or long-term medical use.

learn more https://www.ndtv.com/science/cannabis-compounds-show-potential-against-deadly-fungal-pathogen-in-lab-studies-8587390